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Future Opportunities: Scientist, Target Validation and Exploratory Neurobiology Neurodegeneration

Verge Genomics

Verge Genomics

(Other)
South San Francisco, CA, USA
Posted on Saturday, December 17, 2022
<div><span style="font-size:16pt;">Who We Are</span></div><div><span style="font-size:11pt;">Technology has transformed almost every single aspect of our lives. Yet, it still takes 12 years to develop a drug. Today thousands of diseases affecting hundreds of millions of people have no effective treatment. Accelerating the pace of bringing effective, new medicines to patients is one of the greatest opportunities for humanity. Our mission is to develop better drugs, faster using technology. We have built an end-to-end technology-driven drug discovery platform centered around one of the field’s largest human genomics databases in neuroscience. We use aspects of machine learning to map the complex causes of disease and turn those insights into promising drug candidates on our internal biology and chemistry platforms. We are developing drugs to treat some of the biggest medical challenges today: ALS, Parkinson’s Disease, and Alzheimer’s Disease. Our first drug entered the clinic in October 2022 as a new treatment for ALS and was discovered entirely from our platform. We have raised $134M from top tier investors (e.g. BlackRock, Eli Lilly, Merck, Section 32, Threshold Ventures, Y Combinator, etc) and in 2021 we announced a $706M deal with Eli Lilly. We are a team of data scientists, neuroscientists, and drug developers united around an audacious vision: to build the next Genentech of the digital age. </span></div><div><br></div><div><span style="font-size:18px;">Who You Are</span></div><div><span style="font-size:11pt;">Verge Genomics is seeking scientists of all levels in its Target Validation and Exploratory Neurobiology team. We will consider Senior Research Associates as well. You will make important contributions to our mission by identifying and validating novel genetic targets to fill Verge’s pipeline of small molecules and novel therapeutic modalities, such as gene therapies and ASOs. </span></div><div><br></div><div><span style="font-size:11pt;">In this position, you will serve as a key link between our computational and drug discovery teams, by investigating the biology of neurodegenerative disorders, such as Parkinson’s disease and ALS. You will implement functional genomics technologies, phenotypic assays such as high content imaging, multi-electrode arrays and ‘omics’ assays (e.g., RNAseq, proteomics) to explore gene function in disease relevant brain cell models. To reach these goals, you will develop human induced pluripotent stem cell (iPSC) technology to generate and study neurons neurodegenerative disorders in astrocytes, microglia, oligodendrocytes, and organoids.</span></div><div><br></div><div><span style="font-size:14.6667px;">These are future opportunities positions to help build our pipeline for early 2023. We encourage scientists of all levels to apply.</span></div>
Verge Genomics is an equal opportunity employer.
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